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Reciprocal Interactions Between Wakefulness and Sleep Influence Global and Regional Brain Activity

  作者 Muto, V; Mascetti, L; Matarazzo, L; Kusse, C; Foret, A; Shaffii-Le Bourdiec, A; Vandewalle, G; Dijk, DJ; Maquet, P  
  选自 期刊  Current Topics in Medicinal Chemistry;  卷期  2011年11-19;  页码  2403-2413  
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[摘要]Reciprocal interactions between wakefulness and sleep substantially influence human brain function in both states of vigilance. On the one hand, there is evidence that regionally-specialized brain activity during wakefulness is modulated by the interaction between a local use-dependent buildup of homeostatic sleep pressure and circadian signals. On the other hand, brain activity during sleep, although mainly constrained by genuine sleep oscillations, shows wake-dependent regionally-specific modulations, which are involved in the dissipation of local homeostatic sleep pressure and memory consolidation.

 
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