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Assembly of N,N-Disubstituted Hydrazines and 1-Aryl-1H-indazoles via Copper-Catalyzed Coupling Reactions

  作者 XIONG XIAODONG; JIANG YONGWEN; MA DAWEI  
  选自 期刊  Organic Letters;  卷期  2012年14-10;  页码  2552-2555  
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[摘要]Cul-catalyzed coupling of N-acyl-N-substituted hydrazines with aryl iodides takes place at 60-90 degrees C to afford N-acyl-N,N-disubstituted hydrazines regioselectively and thereby gives a facile method for assembling N,N-diaryl hydrazines. N-Acyl-N-substituted hydrazines can also react with 2-bromoarylcaibonylic compounds at 60-125 degrees C under the catalysis of Cul/4-hydroxy-L-proline to provide 1-aryl-1H-indazoles.

 
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