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Access to Cyclic or Branched Peptides Using Bis(2-sulfanylethyl)amido Side-Chain Derivatives of Asp and Glu

  作者 BOLL EMMANUELLE; DHEUR JULIEN; DROBECQ HERVE; MELNYK OLEG  
  选自 期刊  Organic Letters;  卷期  2012年14-9;  页码  2222-2225  
  关联知识点  
 

[摘要]Bis(2-sulfanylethyl)amido (SEA) side-chain derivatives of aspartic and glutamic acids enable the synthesis of tail-to-side chain cyclic or branched peptides using standard Fmoc-SPPS followed by SEA native peptide ligation.

 
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