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Hypoxylonols C-F, Benzo[j]fluoranthenes from Hypoxylon truncatum

  作者 Fukai, M; Tsukada, M; Miki, K; Suzuki, T; Sugita, T; Kinoshita, K; Takahashi, K; Shiro, M; Koyama, K  
  选自 期刊  Journal of natural products;  卷期  2012年75-1;  页码  22-25  
  关联知识点  
 

[摘要]Four novel benzo[j]fluoranthene derivatives, hypoxylonols C (3), D (4), E (5), and F (6), have been isolated from the mushroom Hypoxylon truncatum, together with two known benzo[j]fluoranthene derivatives, hypoxylonols A (1) and B (2). The structures were established by analysis of NMR spectroscopic data and X-ray diffraction data. Compounds 4 and 5 showed antiproliferative activity against HUVECs (human umbilical vein endothelial cells) and HUAECs (human umbilical artery endothelial cells).

 
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