ONE-POT SYNTHESIS OF 2-NITROOXYALKOXYLATED INOSINE ANALOGS USING CYCLIC ETHER AND ISOAMYL NITRITE

[摘要]：An O(6)-methylguanosine derivative (1) was treated with isoamyl nitrite in the presence of a cyclic ether such as trimethylene oxide, tetrahydrofuran, or tetrahydropyran to give the corresponding 2-nitrooxyalkoxy-6-methoxypurine riboside derivatives (2a-c).

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