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[摘要]:beta-Actin mRNA requires the RNA-binding protein ZBP1 for trafficking to distal regions of the cytoplasm. In this issue of The EMBO Journal, Donnelly et al show that ZBP1 is a limiting and essential factor for adult axonal regeneration in vivo, via trafficking of additional mRNAs. These findings highlight a complex web of interactions between RNA-binding proteins and cargo mRNAs. |
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