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Protein dynamical transition at 110 K

  作者 Kim, CU; Tate, MW; Gruner, SM  
  选自 期刊  Proceedings of the National Academy of Sciences of the United States of America;  卷期  2011年108-52;  页码  20897-20901  
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[摘要]Proteins are known to undergo a dynamical transition at around 200 K but the underlying mechanism, physical origin, and relationship to water are controversial. Here we report an observation of a protein dynamical transition as low as 110 K. This unexpected protein dynamical transition precisely correlated with the cryogenic phase transition of water from a high-density amorphous to a low-density amorphous state. The results suggest that the cryogenic protein dynamical transition might be directly related to the two liquid forms of water proposed at cryogenic temperatures.

 
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