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Novel 1,5-naphthyridine PI3K delta inhibitors, an evaluation of WO2011075628

  作者 Norman, P  
  选自 期刊  Expert Opinion on Therapeutic Patents;  卷期  2011年21-11;  页码  1805-1810  
  关联知识点  
 

[摘要]A small series of aryl(1-arylamino) ethyl, 1,5-naphthyridine derivatives that selectively inhibit PI3K delta was prepared. The compounds are claimed to be useful in the treatment of cancer, inflammatory and autoimmune diseases. The compounds represent further variations around a structural motif explored in a number of previous applications by the applicant.

 
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