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[摘要]：The impact of consuming curcuminoids containing curcumin at 500mg/day and 6g/day for 7days on plasma antioxidant capacity and serum cholesterol level were determined by using vitamin E 200IU/day consumption as a comparison. Group A and group B subjects consumed 500mg and 6g curcumin, respectively, but group C subjects consumed vitamin E 200IU. By using the oxygen radical absorbance capacity (ORAC) assay, it was found that plasma antioxidant capacity of group A rose from a baseline of 13% to 24% on day 1 and day 7, as against a 19-20% increase for group B. Serum cholesterol and triglyceride levels were significantly decreased after curcumin treatment at 500mg/day. By consuming vitamin E, both ORAC values and plasma alpha-tocopherol concentrations were significantly increased, but only very slight responses on serum cholesterol or triglyceride levels were observed. It is therefore suggested that curcumin supplement would not be appropriate for healthy people except for reducing serum cholesterol or triglyceride levels. The dosage of a daily curcumin supplement at 500mg is more effective than 6g, although vitamin E is also considered to be an effective antioxidant supplement. Copyright (C) 2011 John Wiley & Sons, Ltd. |
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