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Mechanistic Studies on a New Catalyst System (CuI-NaHSO(4)center dot SiO(2)) Leading to the One-Pot Synthesis of Imidazo[1,2-a]pyridines from Reactions of 2-Aminopyridines, Aldehydes, and Terminal Alkynes

  作者 MISHRA SARITA; GHOSH RINA  
  选自 期刊  Synthesis;  卷期  2011年-21;  页码  3463-3470  
  关联知识点  
 

[摘要]One-pot reactions of aldehydes, 2-aminopyridines, and terminal alkynes, in the presence of the copper(I) iodide-NaHSO(4)center dot SiO(2) combination catalyst in refluxing toluene, generate the corresponding imidazo[1,2-a]pyridines in high to excellent yields; the mechanism has been studied.

 
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