【文章名】Mechanistic Studies on a New Catalyst System (CuI-NaHSO(4)center dot SiO(2)) Leading to the One-Pot Synthesis of Imidazo[1,2-a]pyridines from Reactions of 2-Aminopyridines, Aldehydes, and Terminal Alkynes
Mechanistic Studies on a New Catalyst System (CuI-NaHSO(4)center dot SiO(2)) Leading to the One-Pot Synthesis of Imidazo[1,2-a]pyridines from Reactions of 2-Aminopyridines, Aldehydes, and Terminal Alkynes
[摘要]:One-pot reactions of aldehydes, 2-aminopyridines, and terminal alkynes, in the presence of the copper(I) iodide-NaHSO(4)center dot SiO(2) combination catalyst in refluxing toluene, generate the corresponding imidazo[1,2-a]pyridines in high to excellent yields; the mechanism has been studied.