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The Continuous-Flow Synthesis of Styrenes Using Ethylene in a Palladium-Catalysed Heck Cross-Coupling Reaction

  作者 BOURNE SAMUEL L; KOOS PETER; OBRIEN MATTHEW; MARTIN BENJAMIN; SCHENKEL BERTHOLD; BAXENDALE IAN R; LEY STEVEN V  
  选自 期刊  SYNLETT;  卷期  2011年-18;  页码  2643-2647  
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[摘要]We report a palladium-catalysed ethylene Heck reaction for the vinylation of aryl iodides using a tube-in-tube gas-liquid reactor. The flow process afforded various styrenes in short reaction times, employing moderate ethylene pressure.

 
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