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Enantioselective and Regioselective Indium(III)-Catalyzed Addition of Pyrroles to Isatins

  作者 GUTIERREZ ELISA G; WONG CASEY J; SAHIN AZIZA H; FRANZ ANNALIESE K  
  选自 期刊  Organic Letters;  卷期  2011年13-21;  页码  5754-5757  
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[摘要]The indium(III)-catalyzed enantioselective and regioselective addition of pyrroles to isatins is described. The effects of metal and solvent on the reactivity and selectivity are compared and discussed, demonstrating that the indium(III)-indapybox complex provides the most effective catalyst. A case of divergent reactivity between pyrroles and indoles is presented.

 
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