| |
[摘要]：Over the years a wide variety of gamma-pyrone-containing natural products have been isolated and a number of their total syntheses accomplished. This review discusses a selection of synthetic strategies towards the total synthesis of some of these complex metabolites. 1 Introduction 2 Polyketide Biosynthesis 3 Common Methodology for gamma-Pyrone Construction 4 Synthetic Approaches 5 Polyunsaturated gamma-Pyrones 5.1 Conjugated Polyenes: Cyercenes and Placidenes 5.2 Non-Conjugated Polyenes: Actinopyrone and Verticipyrone 6 Polyoxygenated Side-Chain 6.1 Baconipyrones A-D, Siphonarins A and B 6.2 Auripyrones A and B 7 Nitrophenyl gamma-Pyrones and Derivatives 7.1 Aureothin, N-Acetylaureothamine 8 Electrocyclisation Reactions in gamma-Pyrone Natural Product Synthesis 8.1 The Tridachione Family 8.2 The Tridachiahydropyrones 8.3 Spectinabilin and the 'SNF' Compounds 9 Conclusions |
|
