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Organocatalytic Asymmetric Strecker Reaction of Di- and Trifluoromethyl Ketoimines. Remarkable Fluorine Effect

  作者 LIU YUNLIN; SHI TAODA; ZHOU FENG; ZHAO XIAOLI; WANG XIN; ZHOU JIAN  
  选自 期刊  Organic Letters;  卷期  2011年13-15;  页码  3826-3829  
  关联知识点  
 

[摘要]A highly enantioselective Strecker reaction of difluoromethyl and trifluoromethyl ketoimines was developed. Remarkable fluorine effect on the reactivity and selectivity is observed and discussed.

 
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