TWO NEW XANTHONE GLUCOSIDES FROM SWERTIA MUSSOTII FRANCH

[摘要]：Two new xanthone glucosides, 1-O-beta-D-glucopyranosyl-3,5,6-trimethoxy-xanthone (1), 1-O-[beta-D-xylopyranosyl-(1 -> 6)-beta-D-glucopyranosyl]-3,5,6-trimethoxy-xanthone (2), were isolated from a EtOH extract of the overground parts of Swertia mussotii Franch, which is a traditional Tibet medicine. Their structures were elucidated by spectroscopic methods as well as by chemical studies. Compound 1 showed alpha-glucosidase inhibitory activity, while compound 2 showed DPP-IV (Dipeptidyl Peptidase IV) inhibitory activity.

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