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SYNTHESIS OF THE IDENTICAL LINKER MODE TWIN-DRUG TYPE C2-SYMMETRICAL MOLECULES

  作者 FUJISAKI FUMIKO; USAMI HARUKA; NAKASHIMA SAYA; IWASHITA SHIOMI; KUROSE YURIE; KASHIGE NOBUHIRO; MIAKE FUMIO; SUMOTO KUNIHIRO  
  选自 期刊  Heterocycles;  卷期  2011年83-8;  页码  1843-1851  
  关联知识点  
 

[摘要]In connection with our studies on antibacterial active compounds against gram-positive (Staphylococcus aureus) and gram-negative (Escherichia colt) strains, some molecular modifications were attempted. In this study, molecular transformations of aminoguanidines and related amines to the represented C2-symmetrical molecules (Aa-b, Ba-b, and Ca-b) were investigated. In addition, some C3-symmetrical compounds (Da-b) were also prepared.

 
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