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Resonance light scattering as a powerful tool for sensitive detection of beta-amyloid peptide by gold nanoparticle probes

  作者 WANG CHENGKE; LIU DIANJUN; WANG ZHENXIN  
  选自 期刊  Chemical Communications;  卷期  2011年47-33;  页码  9339-9341  
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[摘要]A novel biosensing strategy has been developed for sensitive detection of beta-amyloid 1-42 (A beta(1-42)) down to the ng mL(-1) level in both aqueous solution and diluted human plasma, which is based on measuring changes in resonance light scattering of streptavidin functionalized gold nanoparticles as a function of the concentration of A beta(1-42) with a conventional spectrofluorometer.

 
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