[摘要]:Reaction of the title substrate with methylhydrazine yields, via a domino process, HF elimination-beta-addition/elimination-cyclocondensation, to 3-hydroxy-5-trifluoromethylpyrazol-4-ylacetic acid derivatives. In a similar domino process, reaction with benzamidine led mainly to ethyl 4-oxo-2-phenyl-6-trifluoromethylpyrimidin-4-yl acetate. While pyrazole was obtained in high yield via a totally chemo- and regioselective process, reaction with amidine led to a mixture of regioisomers.