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Synthesis of 8-Arylquinolines via One-Pot Pd-Catalyzed Borylation of Quinoline-8-yl Halides and Subsequent Suzuki-Miyaura Coupling

  作者 ZHANG YONGDA; GAO JOE; LI WENJIE; LEE HEEWON; LU BRUCE Z; SENANAYAKE CHRIS H  
  选自 期刊  Journal of Organic Chemistry;  卷期  2011年76-15;  页码  6394-6400  
  关联知识点  
 

[摘要]A one-pot process has been developed for the synthesis of 8-arylquinolines via Pd-catalyzed borylation of quinoline-8-yl halides and subsequent Suzuki-Miyaura coupling with aryl halides using n-BuPAd(2) as ligand. Yields of up to 98% were obtained.

 
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