The Cdk4-E2f1 pathway regulates early pancreas development by targeting Pdx1(+) progenitors and Ngn3(+) endocrine precursors

[摘要]：Cell division and cell differentiation are intricately regulated processes vital to organ development. Cyclin-dependent kinases (Cdks) are master regulators of the cell cycle that orchestrate the cell division and differentiation programs. Cdk1 is essenti

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