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Xylarenones C-E from an Endophytic Fungus Isolated from Alibertia macrophylla

  作者 de Oliveira, CM; Silva, GH; Regasini, LO; Flausino, O; Lopez, SN; Abissi, BM; Berlinck, RGD; Sette, LD; Bonugli-Santos, RC; Rodrigues, A; Bolzani, VD; Araujo, AR  
  选自 期刊  Journal of natural products;  卷期  2011年74-6;  页码  1353-1357  
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[摘要]Xylarenones C-E (2-4), three new eremophilane sesquiterpenes, have been isolated from solid substrate cultures of a Camarops-like endophytic fungus isolated from Alibertia macrophylla. The structures were elucidated by analysis of spectroscopic data. Compounds were evaluated in subtilisin and pepsin protease assays, and compound 2 showed potent inhibitory activity against both proteases.

 
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