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Developing Novel Organocatalyzed Aldol Reactions for the Enantioselective Synthesis of Biologically Active Molecules

  作者 BHANUSHALI MAYUR; ZHAO CONGGUI  
  选自 期刊  Synthesis;  卷期  2011年-12;  页码  1815-1830  
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[摘要]The aldol reaction is one of the most important methods for the formation of carbon-carbon bonds. Because of its significance and utility, asymmetric versions of this reaction have been realized with different approaches in the past. Over the last decade, the area of organocatalysis has made significant progress. As one of most studied reactions in organocatalysis, the organocatalyzed aldol reaction has emerged as a powerful tool for the synthesis of a large number of useful products in optically enriched forms. In this review, we summarize our efforts on the development of novel organocatalyzed aldol reactions for the enantioselective synthesis of biologically active molecules.

 
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