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Optically Pure Polyfluoroalkanesulfinamides: Synthesis and Application as Promising and Monitorable Chiral Auxiliaries

  作者 LIU LIJUAN; CHEN LINGJUN; LI PENG; LI XIAOBO; LIU JINTAO  
  选自 期刊  Journal of Organic Chemistry;  卷期  2011年76-11;  页码  4675-4681  
  关联知识点  
 

[摘要]Efficient synthesis of enantiopure polyfluoroalkanesulfinamides (PFSAs) has been achieved. Their application as novel chiral auxiliaries with an electron-withdrawing and F-19 NMR monitorable polyfluoroalkyl group was initially demonstrated in an asymmetric Strecker reaction under mild conditions.

 
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