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Regioselective Monoalkylation of Dimethyl Alkylidenesuccinates: Simple Approach to Dialkyl-Substituted Maleic Anhydrides Including Chaetomellic Acid A

  作者 KSHIRSAGAR UMESH A; ARGADE NARSHINHA P  
  选自 期刊  Synthesis;  卷期  2011年-11;  页码  1804-1808  
  关联知识点  
 

[摘要]Natural and nonnatural dialkylmaleic anhydrides were readily prepared from dimethyl alkylidenesuccinates by sodium hexamethyldisilazide-induced selective monoalkylation followed by base-catalyzed hydrolysis.

 
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