ANTIFEEDANT ACTIVITIES OF TUTIN AND ANDROGRAPHOLIDE DERIVATIVES AGAINST MYTHIMNA SEPARATA

[摘要]：Nine andrographolide derivatives (A2, A3a-b, A4a-e, A5) were synthesized to study the antifeedant activities of these derivatives and tutin against Mythimna separata. Compared with tutin, the nine derivatives exhibited better antifeedant activities, and six of them showed different mortality effects. It was concluded that the potent insecticidal agents are A2 (14-deoxy-11,12-didehydro-andrographolide), A4d (15-fluorobenzylidene-14-deoxy-11,12-didehydro-andrographolide) and A4e (15-bromoacylbenzylidene-14-deoxy-11,12-didehydro-andrographolide).

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