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Acridine derivatives: a patent review (2009--2010)

  作者 Kaur, J; Singh, P  
  选自 期刊  Expert Opinion on Therapeutic Patents;  卷期  2011年21-4;  页码  437-454  
  关联知识点  
 

[摘要]Areas covered: In this review, acridine-based functional molecules and patents of acridine derivatives filed from 2009 to 2010 are discussed. The latest information about the medical importance of new acridine-based molecules is also discussed (e.g., materials with sensing and electrical/thermal properties). Expert opinion: The tricyclic aromatic heterocyclic structure of acridine has a lot of potential for biological and material utilization. The versatility of fluorescent acridines could be further enhanced by introducing amino-acid chains or other polar substituents on the central moiety, which due to increased water solubility could increase their effectiveness under physiological conditions.

 
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