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Asymmetric Direct Michael Addition of Acetophenone to alpha,beta-Unsaturated Aldehydes

  作者 LI WENJUN; WU WENBIN; YANG JUANJUAN; LIANG XINMIAO; YE JINXING  
  选自 期刊  Synthesis;  卷期  2011年2011-7;  页码  1085-1091  
  关联知识点  
 

[摘要]The asymmetric direct Michael addition of alpha,beta-unsaturated aldehydes with acetophenone catalyzed by a Jorgensen-Hayashi catalyst in methanol was developed and the corresponding Michael products of delta-keto aldehydes could be afforded in up to 82% yield and 98% ee.

 
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