A Straightforward Synthetic Approach to beta-Substituted Phenylalanines via Ring Opening of Aryl Epoxides

[摘要]：Regioselective ring opening of aryl epoxides with chelated amino acid ester enolates gives rise to beta-hydroxymethyl phenylalanine derivatives. This methodology allows straightforward access to a wide range of modified beta-phenylalanine derivatives, which can be subjected to further transformations.

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