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Practical and Novel One-Pot Protocol for the Synthesis of Highly Functionalized Pyridinols and Pyrido[1,2-a]-Fused 1,3-Diazaheterocycles

  作者 ALIZADEH ABDOLALI; REZVANIAN ATIEH  
  选自 期刊  SYNLETT;  卷期  2011年-8;  页码  1105-1108  
  关联知识点  
 

[摘要]A novel and efficient protocol for the generation of substituted pyridinols and pyrido[1,2-a]-fused 1,3-diazaheterocycles from primary amine or 1, n-diamine, nitro ketene dithioacetal [1, l-bis(methylthio)-2-nitroethene] and dibenzylideneacetone as starting materials in a one-pot process combining a Michael addition reaction and nucleophilic addition under mild condition in high yield has been developed.

 
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