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Copper-Catalyzed Annulative Amination of ortho-Alkynylphenols with Hydroxylamines: Synthesis of 3-Aminobenzofurans by Umpolung Amination Strategy

  作者 HIRANO KOJI; SATOH TETSUYA; MIURA MASAHIRO  
  选自 期刊  Organic Letters;  卷期  2011年13-9;  页码  2395-2397  
  关联知识点  
 

[摘要]A room temperature copper-catalyzed annulative amination of ortho-alkynylphenols with electrophilic amination reagents, O-acylated hydroxylamines, proceeds efficiently to provide the corresponding 3-aminobenzofurans of biological and pharmaceutical interest.

 
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