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[摘要]：A new xanthone derivative, garcinexanthone F (1), which was found to possess an alpha,beta-unsaturated gamma-lactone moiety, and a new bisxanthone, bigarcinenone B (2), with a terpene bridge providing the xanthone-xanthone linkage, were isolated from the bark of Garcinia xanthochymus. Their structures were elucidated by spectroscopic methods, especially 2D-NMR techniques. The antioxidant assay in vitro showed that compounds 1 and 2 exhibited significant scavenging activities against 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical with IC50 values of 22.32 and 20.14 mu m, and against HO center dot. radical with IC50 values of 1.16 and 2.85 mu m, respectively. |
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