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Silica Nanoparticles as a Highly Efficient Catalyst for the One-Pot Synthesis of 2-Hydroxyacetamide Derivatives from Isocyanides and Electron-Poor Aromatic Aldehydes

  作者 Ramazani, A; Mahyari, A; Lashgari, H; Slepokura, K; Lis, T  
  选自 期刊  Helvetica Chimica Acta;  卷期  2011年94-4;  页码  611-622  
  关联知识点  
 

[摘要]Reaction of an isocyanide with an electron-poor aromatic aldehyde in the presence of silica nanoparticles (silica NP; ca. 42 nm) proceeds smoothly at room temperature to afford 2-hydroxyacetamide derivatives in high yields (Scheme 1 and Table 1).

 
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