【文章名】Silica Nanoparticles as a Highly Efficient Catalyst for the One-Pot Synthesis of 2-Hydroxyacetamide Derivatives from Isocyanides and Electron-Poor Aromatic Aldehydes
Silica Nanoparticles as a Highly Efficient Catalyst for the One-Pot Synthesis of 2-Hydroxyacetamide Derivatives from Isocyanides and Electron-Poor Aromatic Aldehydes
作者
Ramazani, A; Mahyari, A; Lashgari, H; Slepokura, K; Lis, T
[摘要]:Reaction of an isocyanide with an electron-poor aromatic aldehyde in the presence of silica nanoparticles (silica NP; ca. 42 nm) proceeds smoothly at room temperature to afford 2-hydroxyacetamide derivatives in high yields (Scheme 1 and Table 1).