Synthesis and Functionalization of 3-Alkylidene-1,2-diazetidines Using Transition Metal Catalysis

[摘要]：An efficient two-step synthesis of a wide range of 3-methylene-1,2-diazetidines has been developed through application of a Cu(I)-catalyzed 4-exo ring closure. The double bond of this new class of strained heterocycle can be functionalized in a stereocontrolled manner by using palladium-catalyzed Heck reactions. Moreover, chemoselective reduction of 3-alkylidene-1,2-diazetidines gives access to saturated 1,2-diazetidines and vicinal diamines.

[全文传递流程]：

一般上传文献全文的时限在1个工作日内