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Anodic Coupling Reactions: Exploring the Generality of Curtin-Hammett Controlled Reactions

  作者 REDDEN ALISON; MOELLER KEVIN D  
  选自 期刊  Organic Letters;  卷期  2011年13-7;  页码  1678-1681  
  关联知识点  
 

[摘要]Intramolecular anodic olefin coupling reactions can be compatible with the presence of dithioketal protecting groups even though the dithioketal oxidizes at a lower potential than either of the groups participating in the cyclization. In such cases, product formation is controlled by the Curtin-Hammett Principle. In this study, the generality of such reactions is examined along with the use of alternative reaction conditions to suppress unwanted side reactions.

 
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