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Lewis Acid-Mediated Michaelis-Arbuzov Reaction at Room Temperature: A Facile Preparation of Arylmethyl/Heteroarylmethyl Phosphonates

  作者 RAJESHWARAN GANESAN GOBI; NANDAKUMAR MEGANATHAN; SURESHBABU RADHAKRISHNAN; MOHANAKRISHNAN ARASAMBATTU K  
  选自 期刊  Organic Letters;  卷期  2011年13-6;  页码  1270-1273  
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[摘要]A facile preparation of arylmethyl and heteroarylmethyl phosphonate esters was achieved involving a Lewis acid mediated Michaelis-Arbuzov reaction at room temperature. Interaction of arylmethyl halides/alcohols with triethyl phosphite in the presence of Lewis acid at room temperature afforded phosphonate esters in good yields.

 
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