Optical Resolution and Structure Determination of New Indolizidine Alkaloids from Elaeocarpus sphaericus

[摘要]：Two new indolizidine alkaloids, (+/-)-3-oxoisoelaeocarpine (1) and (+/-)-elaeocarpine N-oxide (2), along with three known alkaloids, (+/-)-isoelaeocarpine (3), (+/-)-elaeocarpine (4), and (-)-isoelaeocarpiline (5), were isolated from an EtOH extract of the branches and leaves of Elaeocarpus sphaericus. The structures of these compounds were determined by spectroscopic and chemical methods. Furthermore, enantiomers of compounds 1 and 3 were separated on a chiral CD-Ph column, and their absolute configurations were determined by TD-DFT (time-dependent density-functional theory) quantum-chemical calculations of their electronic circular dichroism (ECD) spectra.

[全文传递流程]：

一般上传文献全文的时限在1个工作日内