A FACILE SYNTHESIS OF 2-SUBSTITUTED 2,3-DIHYDRO-4(1H)-AZULENO[1,2-d]PYRIMIDINONES

[摘要]：A facile, efficient and novel approach to access 2-substituted 2,3-dihydro-4(1H)-azuleno[2,1-d]pyrimidinones was developed by condensation of methyl 2-amino-3-carbamoylazulene-1-carboxylate with ketones or aryl aldehydes in the 2,2,2-trifluoroethanol catalyzed by p-toluenesulfonic acid.

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