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EFFICIENT SYNTHESIS OF FUNCTIONALIZED DIAZACYCLOPENTA[C]PENTALENE WITH MULTIPLE INTERMOLECULAR INTERACTIONS IN CRYSTAL

  作者 KUDRYAVTSEV KONSTANTIN V  
  选自 期刊  Heterocycles;  卷期  2011年83-2;  页码  323-330  
  关联知识点  
 

[摘要]Atom economic synthesis of functionalized polysubstituted racemic diazacyclopenta[c]pentalene 7 has been developed using sequential organocatalytic 1,3-dipolar cycloaddition of azomethine ylide with maleic anhydride and three successive amide bonds formation induced by interaction of 4-fluorobenzylamine with heterocyclic anhydride 5. Enantiomers of 7 are connected by Cl-pi, H center dot center dot center dot F and C=O center dot center dot center dot H intermolecular interactions in crystal.

 
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