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[摘要]：A new cyclic lipopeptide, marihysin A (1), along with the three known cyclodipeptides cyclo(Ala-Ile) (2), cyclo(Ala-Leu) (3), and cyclo(Ala-Tyr) (4), was isolated from the fermentation broth of the marine microorganism Bacillus marinus B-9987 isolated from the tissues of rhizophere of Suaeda salsa in the intertidal zone of the Bohai Bay of P. R. China. Marihysin A (1) was established to be cyclo(Pro-Gln-Asn(1)-Ser-Asn(2)-Tyr-Asn(3)-beta-aminotetradecanoic acid) by spectroscopic analysis, and it exhibits broad-spectrum but low activity against plant pathogens as determined by antifungal bioassay. |
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