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[摘要]：The aim of this study was to investigate the bioavailability of anthocyanins from chokeberry juice with a dietary-relevant dose of anthocyanins. Thirteen healthy volunteers consumed chokeberry juice providing 0.8 mg of anthocyanins/kg of body weight. Before and after juice consumption, blood and urine were collected. Concentration of anthocyanins was measured with HPLC-PDA-MS-ESI. Cyanidin-3-galactoside comprised 66% of total chokeberry anthocyanins. Eight cyanidin derivatives were found In blood and urine after juice consumption. The maximum plasma anthocyanin concentration of 32.7 +/- 2.9 nmol/L was reached at 1.3 +/- 0.1 h after juice consumption. The anthocyanins' urine excretion rate (62.9 +/- 5.0 nmol/h) was the highest within the first 2 h. In total, 0.25 +/- 0.02% of the ingested anthocyanins was excreted by the renal route during 24 h, mainly as metabolites of cyanidin. According to these observations, after consumption of a dietary-relevant dose of anthocyanins as natural chokeberry juice, anthocyanins and their metabolites were present in plasma and urine of volunteers. |
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