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Synthesis of Tetrahydroisoquinolines via Cascade Reductive Amination of Isochromenylium Tetrafluoroborate with Primary Amines

  作者 LIAO HONGZE; HU ZHILONG; CUI KAI; JIAO JIAO; QIN YONG; YAO ZHUJUN  
  选自 期刊  Synthesis;  卷期  2010年-20;  页码  3474-3480  
  关联知识点  
 

[摘要]Reactions of isochromenylium tetrafluoroborates with various primary amines have been investigated under reductive amination conditions. The established cascade methodology provides a convenient one-step synthesis of various tetrahydroisoquinoline derivatives under mild conditions.

 
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