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Lactam Enolate-Pyridone Addition: Synthesis of 4-Halocytisines

  作者 DURKIN PATRICK; MAGRONE PIETRO; MATTHEWS STELLA; DALLANOCE CLELIA; GALLAGHER TIMOTHY  
  选自 期刊  SYNLETT;  卷期  2010年-18;  页码  2789-2791  
  关联知识点  
 

[摘要]The application of a lactam enolate-pyridone addition sequence, originally developed for cytisine, has been applied successfully to generate the first examples of 4-halocytisines. Variation of the lactam component provides cyfusine and 4-fluorocyfusine.

 
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