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SYNTHESIS AND ANTIMICROBIAL EVALUATION OF SOME NEW PYRIDINE BASED HETEROCYCLES

  作者 DARWISH ELHAM S; KHEDER NABILA A; FARAG AHMAD M  
  选自 期刊  Heterocycles;  卷期  2010年81-10;  页码  2247-2256  
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[摘要]A facile and convenient synthesis of pyridine, pyridazine, 2(3H)-1,3,4-thiadiazole and pyrazole derivatives incorporating a pyridine-2-ylcarboxamido moiety via the versatile, readily accessible 3-oxo-N-(pyridin-2-yl)butanamide is described. Antimicrobial evaluation of some selected examples from the synthesized products was carried out and showed moderate activity.

 
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