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One-Pot Three-Step Synthesis of 1,2,3-Triazoles by Copper-Catalyzed Cycloaddition of Azides with Alkynes formed by a Sonogashira Cross-Coupling and Desilylation

  作者 FRISCOURT FREDERIC; BOONS GEERTJAN  
  选自 期刊  Organic Letters;  卷期  2010年12-21;  页码  4936-4939  
  关联知识点  
 

[摘要]A microwave-assisted, one-pot, three-step Sonogashira cross-coupling-desilylation-cycloaddition sequence was developed for the convenient preparation of 1,4-disubstituted 1,2,3-triazoles starting from a range of halides, acyl chlorides, ethynyltrimethylsilane, and azides.

 
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