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BIOINFORMATIC APPROACHES TO THE STUDY OF CHLAMYDIAL DISEASES

  作者 Rabasseda, X; Morre, SA; Ouburg, S  
  选自 期刊  Drugs of today;  卷期  2009年45-11;  页码  173-187  
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[摘要]The combination of bioinformatics, genomics and proteomics is a rapidly expanding research field that has now become essential for the investigation of biological, cellular and molecular phenomena, both in terms of established facts and in prediction models based on simulations, and therefore can greatly contribute to the development of potential new therapeutic approaches. This article provides numerous, well-known examples illustrating the importance of bioinformatics in modem biological and medical research in the field of infectious diseases, specifically Chlamydia trachomatis infection. Specialized chlamydia databases and analysis programs and the information they contain provide the opportunity for understanding and identifying key processes and phenomeno associated with the unique infection cycle of chlamydia, and ore paving the way towards the development of novel diagnostic and therapeutic tools. Bioinformatics may provide the clues necessary for a true breakthrough in the fight against chlamydial diseases: the development of a vaccine.

 
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