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Synthesis and biological activity of n-butylphthalide derivatives

  作者 Wang, W; Cha, XX; Reiner, J; Gao, Y; Qiao, HL; Shen, JX; Chang, JB  
  选自 期刊  European Journal of Medicinal Chemistry;  卷期  2010年45-5;  页码  1941-1946  
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[摘要]A series of n-butylphthalide derivatives were designed and synthesized. The in vitro activities of these compounds were evaluated by a resting tension of isolated rat thoracic aorta ring assay. Compounds 4g and 41 were found to be more active than n-butylphthalide. (C) 2010 Elsevier Masson SAS. All rights reserved.

 
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