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Tirucallane-Type Alkaloids from the Bark of Dysoxylum laxiracemosum

  作者 Zhang, XY; Li, Y; Wang, YY; Cai, XH; Feng, T; Luo, XD  
  选自 期刊  Journal of natural products;  卷期  2010年73-8;  页码  1385-1388  
  关联知识点  
 

[摘要]Eight novel tirucallane-type alkaloids (1-8) and 11 known compounds were isolated from a methanol extract of the bark of Dysoxylum laxiracemosum. The structures of 1-8 were elucidated using extensive NMR spectrometric and mass spectroscopic methods. Compounds 1 and 5, named laxiracemosins A and E, showed significant cytotoxicity against five human cancer cell lines.

 
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