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Interconvertible Eudesmanolides Containing a 6,12-Hemiketal Function from Salvia castanea DIELS f. tomentosa STIB

  作者 Xu, G; Peng, LY; Shen, XL; Zhao, QS  
  选自 期刊  Helvetica Chimica Acta;  卷期  2010年93-9;  页码  1773-1778  
  关联知识点  
 

[摘要]Two new eudesmanolide sesquiterpenoids containing a hemiacetal function, castanins G and H (1 and 2), were obtained as a pair of interconvertible isomers from the aerial parts of Salvia castanea DIELS f. tomentosa STIB. and separated as their uninterconvertible acetates 3 and 4. Their structures were elucidated by unequivocal interpretation and comparative analysis of the NMR and MS data of the mixture 1/2 and of their acetates 3 and 4. respectively. The inhibitory activity of 3 and 4 toward MCF-7. HeLa, and HepG2 cell lines was also evaluated.

 
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