[摘要]:Two new eudesmanolide sesquiterpenoids containing a hemiacetal function, castanins G and H (1 and 2), were obtained as a pair of interconvertible isomers from the aerial parts of Salvia castanea DIELS f. tomentosa STIB. and separated as their uninterconvertible acetates 3 and 4. Their structures were elucidated by unequivocal interpretation and comparative analysis of the NMR and MS data of the mixture 1/2 and of their acetates 3 and 4. respectively. The inhibitory activity of 3 and 4 toward MCF-7. HeLa, and HepG2 cell lines was also evaluated.