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HSA coated MnO nanoparticles with prominent MRI contrast for tumor imaging

  作者 HUANG JING; XIE JIN; CHEN KAI; BU LIHONG; LEE SEULKI; CHENG ZHEN; LI XINGGUO; CHEN XIAOYUAN  
  选自 期刊  Chemical Communications;  卷期  2010年46-36;  页码  6684-6686  
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[摘要]We report in this Communication a facile, two-step surface modification strategy to achieve manganese oxide nanoparticles with prominent MRI T1 contrast. In a U87MG glioblastoma xenograft model, we confirmed that the particles can accumulate efficiently in tumor area to induce effective T1 signal alteration.

 
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