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Synthesis of N-Arylindazoles and Benzimidazoles from a Common Intermediate

  作者 WRAY BRENDA C; STAMBULI JAMES P  
  选自 期刊  Organic Letters;  卷期  2010年12-20;  页码  4576-4579  
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[摘要]A variety of N-aryl-1H-indazoles and benzimidazoles were synthesized from common arylamino oximes in good to excellent yields The product selectivity depends upon the base used in the reaction, as triethylamine promoted the formation of benzimidazoles, whereas 2-aminopyridine promoted the formation of N-arylindazoles This method is valuable to the synthetic community because both indazoles and benzimidazoles are prevalent in pharmaceuticals

 
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